Search on: WAVE PROTEINS 
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Descriptor English:   Wiskott-Aldrich Syndrome Protein Family 
Descriptor Spanish:   Familia de Proteínas del Síndrome de Wiskott-Aldrich 
Descriptor Portuguese:   Família de Proteínas da Síndrome de Wiskott-Aldrich 
Synonyms English:   WAS Protein Family
WASP-Family Verprolin Homologous Proteins
WAVE Proteins  
Tree Number:   D05.750.078.730.912
D12.776.220.525.912
Definition English:   A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN. 
Indexing Annotation English:   WISKOTT-ALDRICH SYNDROME PROTEIN and WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL are also available
History Note English:   2006(1999) 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   50563 
Unique Identifier:   D051300 

Occurrence in VHL:
 

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